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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYFIP2 All Species: 35.45
Human Site: Y1060 Identified Species: 60
UniProt: Q96F07 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96F07 NP_001032409.2 1278 148399 Y1060 Q N I L P R V Y I K E G E R L
Chimpanzee Pan troglodytes XP_001137120 1278 148380 Y1060 Q N I L P R V Y I K E G E R L
Rhesus Macaque Macaca mulatta XP_001105005 1359 156392 Y1141 Q N I L P R V Y I K E G E R L
Dog Lupus familis XP_536455 1288 149367 Y1070 Q N I L P R V Y I K E G E R L
Cat Felis silvestris
Mouse Mus musculus Q5SQX6 1253 145641 Y1035 Q N I L P R V Y I K E G E R L
Rat Rattus norvegicus NP_001100987 1253 145239 H1036 Q N I L P R V H V K E G E R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508077 1255 145699 Y1037 Q N I L P R V Y I K E G E R L
Chicken Gallus gallus XP_414567 1253 145683 Y1035 Q N I L P R V Y I K E G E R L
Frog Xenopus laevis Q6GQD1 1253 145619 Y1035 Q N I L P R V Y I K E G E R L
Zebra Danio Brachydanio rerio Q90YM8 1253 145156 H1036 Q N I L P R V H V K E G E R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VF87 1291 149242 F1058 Q N I F P R P F C K E N E K P
Honey Bee Apis mellifera XP_395632 1292 149877 Y1058 Q N I L P R P Y C K E G E K P
Nematode Worm Caenorhab. elegans O44518 1262 144995 A1043 P Q P P A R N A Q E Q M K Q L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5S2C3 1283 145467 N1049 G A E G Q I V N A Q D G E S P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 94 99.1 N.A. 97.9 85.8 N.A. 97.6 97.8 96 84.5 N.A. 62.6 65 51 N.A.
Protein Similarity: 100 100 94 99.2 N.A. 98 92.3 N.A. 97.8 98 97.2 91.6 N.A. 77.3 79.1 69.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. 100 100 100 86.6 N.A. 53.3 73.3 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 80 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 0 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 8 86 0 93 0 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 0 0 0 0 0 86 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % H
% Ile: 0 0 86 0 0 8 0 0 58 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 86 0 0 8 15 0 % K
% Leu: 0 0 0 79 0 0 0 0 0 0 0 0 0 0 72 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 86 0 0 0 0 8 8 0 0 0 8 0 0 0 % N
% Pro: 8 0 8 8 86 0 15 0 0 0 0 0 0 0 22 % P
% Gln: 86 8 0 0 8 0 0 0 8 8 8 0 0 8 0 % Q
% Arg: 0 0 0 0 0 93 0 0 0 0 0 0 0 72 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 79 0 15 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _